Novel heterocycles

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2584303

This invention relates to novel compounds of formula (I) and processes for their preparation, their use for of treating diseases, particularly hyperproliferative diseases such as cancer, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly hyperproliferative diseases such as cancer. Wherein m is 0, 1 or 2; R3 is *-O(CH2)n AR, wherein Ar is phenyl, thienyl, furyl, pyrrolyl, thiazolyl, oxazolyl, imidazolyl, pyridyl, pyrimidyl od pyridazinyl, wherein Ar can optionally be substituted.

L'invention se rapporte à de nouveaux composés représentés par la formule (I) et à leur procédés de préparation, à leur utilisation pour traiter des maladies, notamment des maladies d'hyperprolifération telles que le cancer, et à des procédés de fabrication de compositions pharmaceutiques pour le traitement ou la prévention de troubles, notamment de maladies d'hyperprolifération telles que le cancer. m est 0, 1 ou 2; R<sup

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