C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/55 (2006.01) C07D 207/08 (2006.01) C07D 211/60 (2006.01) C07D 211/78 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2217130
A compound of formula (I). The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
La présente invention porte sur un composé de formule (I). La présente invention concerne de nouveaux acides carboxyliques azahétérocycliques N-substitués, et des esters de ces acides, dans lesquels une chaîne alkyle substituée forme une partie du substituant N ou de sels de celui-ci; l'invention concerne aussi des procédés de préparation de ces composés, des compositions les contenant et leur emploi dans le traitement clinique d'états douloureux, hyperalgésiques et/ou inflammatoires dans lesquels les fibres C jouent un rôle pathophysiologique en induisant une douleur ou une inflammation neurogène.
Andersen Henrik Sune
Andersen Knud Erik
Hohlweg Rolf
Jorgensen Tine Krogh
Madsen Peter
Mccarthy Tetrault Llp
Novo Nordisk A/s
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