C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/14 (2006.01) A61K 31/551 (2006.01) A61P 3/10 (2006.01) C07D 403/06 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2712685
The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tau-tomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The inven-tion also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising compounds of Formula I and methods of treating or preventing one or more conditions that may be regulated or normalized via inhibition of dipeptidyl peptidase IV (DPP-IV). Formula I
La présente invention porte sur des nouveaux composés de formule I et sur leurs dérivés, formes tautomères, stéréo-isomères comprenant les isomères R et S, polymorphes, promédicaments, métabolites, sels ou solvates pharmaceutiquement acceptables. L'invention porte également sur les procédés pour la synthèse des nouveaux composés de formule I et de leurs dérivés, formes tautomères, stéréo-isomères, polymorphes, promédicaments, métabolites, sels ou solvates pharmaceutiquement acceptables. La présente invention porte également sur des compositions pharmaceutiques comprenant des composés de formule I et sur des procédés de traitement ou de prévention d'un ou plusieurs états pathologiques qui peuvent être régulés ou normalisés par l'inhibition de la dipeptidyl peptidase IV (DPP-IV).
Das Jagattaran
Jain Rajesh
Magadi Sitaram Kumar
Nanda Gurmeet Kaur
Sharma Sudhir Kumar
Panacea Biotec Limited
Sim & Mcburney
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