Novel heterocyclic compounds as metap-2 inhibitors

Details Novel heterocyclic compounds as metap-2 inhibitors Novel heterocyclic compounds as metap-2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2749970

The invention relates to compounds of formula I, wherein D, X, Y, Z, R and R1 are defined as in claim 1. Said compounds are inhibitors of the methionine aminopeptidase and can be used for the treatment of tumors.

L'invention concerne des composés de formule I, dans laquelle D, X, Y, Z, R et R1 ont les significations indiquées dans la revendication 1, ces composés étant des inhibiteurs de la méthionine-aminopeptidase et pouvant être utilisés pour le traitement de tumeurs.

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