C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/34 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) C07D 209/34 (2006.01) C07D 277/36 (2006.01) C07D 417/10 (2006.01)
Patent
CA 2642650
The present invention relates to novel heterocyclic diphenyl ether and diphenyl amine compounds, derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable solvates thereof and pharmaceutically acceptable compositions containing these singly or in combination. The compounds of the present invention are effective in lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels and are useful in the treatment and / or prophylaxis of diabetes. The compounds of the present invention are effective in treatment of obesity, inflammation, autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and immunological diseases, including the treatment of cancer. Furthermore, the compounds are useful for the treatment of disorders associated with insulin resistance.
L'invention porte sur de nouveaux composés hétérocycliques d'éther de diphényle et de diphényle amine et sur leurs dérivés, analogues, tautomères,stéréoisomères, polymorphes, hydrates, et solvates, et leurs sels et solvates pharmacocompatibles, et sur des préparations pharmacocompatibles les contenant, seuls ou en combinaison. Les composés de l'invention peuvent servir à abaisser le glucose sanguin, l'insuline sérique, les acides gras libres, les niveaux de cholestérol et de glycérides et donc au traitement et à la prophylaxie du diabète. Ils s'avèrent également efficaces pour traiter l'obésité, l'inflammation, les maladies autoimmunes telles que la sclérose en plaques, l'arthrite rhumatoïde et des maladies immunologiques dont le cancer. Ils s'avèrent en outre utiles pour traiter certains troubles liés à la résistance à l'insuline.
Bhattacharya Birendra Kumar
Dey Debendranath
Jayakumar Surendradoss
Nag Abhijeet
Nag Bishwajit
Bexel Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Novel heterocyclic diphenyl ethers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel heterocyclic diphenyl ethers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel heterocyclic diphenyl ethers will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1875274