Novel histidine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/64 (2006.01) A61K 31/4172 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2692824

The present invention is to provide a novel compound which is useful as a pharmaceutical agent such as an analgesic. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention has a very high intermigration into the blood upon oral administration and is very useful as a pharmaceutical agent, especially an analgesic for the treatment of acute or chronic pain diseases and of neuropathic pain diseases.

L'invention vise à proposer un nouveau composé utile comme agent médicamenteux tel qu'un agent analgésique ou autre. A cet effet, l'invention porte sur un nouveau dérivé d'histidine présentant une excellente activité analgésique ou similaire. Administré oralement, le composé possède une excellente pénétration dans le sang, ce qui le rend très utile comme agent médicamenteux, en particulier comme agent analgésique pour traiter une douleur aiguë ou chronique ou une douleur neurogène.

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