C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/68 (2006.01) C07H 21/02 (2006.01)
Patent
CA 2700522
A set of cellular genes that were identified by siRNA screening as being essential for Human Immunodeficiency Virus (HIV) infection. These genes are host cellular factors involved in DNA repair, specifically in the base excision repair pathway.
L'invention porte sur un ensemble de gènes cellulaires qui ont été identifiés par criblage d'ARNsi comme étant essentiels pour une infection par le virus de l'immunodéficience humaine (VIH). Ces gènes sont des facteurs cellulaires d'hôte mis en jeu dans la réparation de l'ADN, de façon spécifique dans la voie de réparation d'une excision de base.
Espeseth Amy S.
Hazuda Daria J.
Xu Min
Zhou Honglin
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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