C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/09 (2010.01) A61K 35/407 (2006.01) A61K 35/76 (2006.01) A61K 39/015 (2006.01) A61K 39/12 (2006.01) A61K 39/29 (2006.01) A61P 31/12 (2006.01) C07K 16/08 (2006.01) C12N 7/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2453100
The invention concerns human hepatoma cell lines, characterised in that they are capable of being naturally infected by parasites and/or viruses; said parasites can be hepatotropic or not, such as Plasmodium or parasites of the genus leishmania and express receptors of the family of Flaviviridae andHepadnaviridae viruses, preferably HBV and HCV. The invention has diagnostic, therapeutic and prophylactic applications.
L'invention concerne des lignées cellulaires d'hépatomes humains, caractérisées en ce qu'elles sont susceptibles d'être infectées naturellement par des parasites et/ou des virus; lesdits parasites pouvant être hépatotropes ou non, tels que le Plasmodium ou les parasites du genre leishmania; et expriment des récepteurs à la famille des virus des Flaviviridae etHepadnaviridae, de préférence le VHB et le VHC. Applications en diagnostic, thérapeutique et prophylaxie.
Gripon Philippe
Guguen-Guillouzo Christiane
Rumin Sylvie
Trepo Christian
Institut National de La Sante Et de La Recherche Medicale (i.n.s
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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