C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 265/12 (2006.01) A61K 31/535 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) C07D 265/22 (2006.01) C07D 265/24 (2006.01) C07D 265/26 (2006.01) C07D 413/04 (2006.01) C07K 5/00 (2006.01)
Patent
CA 2182203
Novel therapeutic agents useful as inhibitors of HLE are provided. The compounds have structural formula (I) wherein R1 through R9, m, n and p are as defined herein. Methods of using the compounds of formula (I) to inhibit serine proteases and to treat physiological conditions and disease states associated with elevated HLE levels are also provided, as are pharmaceutical compositions containing the compounds.
L'invention concerne de nouveaux agents thérapeutiques utiles en tant qu'inhibiteurs de HLE. Les composés présentent la formule structurelle (I), dans laquelle R?1¿ à R?9¿, m, n et p sont définis dans la description. L'invention concerne également des procédés d'utilisation des composés de la formule (I) afin d'inhiber des sérine-protéases et afin de traiter des états physiologiques ainsi que des états pathologiques associés à des niveaux élevés de HLE, ainsi que des compositions pharmaceutiques contenant lesdits composés.
Hiebert Charles K.
Laibelman Alan
Ryan Kenneth J.
Gowling Lafleur Henderson Llp
Sri International
LandOfFree
Novel human leukocyte elastase (hle) inhibitors, and related... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel human leukocyte elastase (hle) inhibitors, and related..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel human leukocyte elastase (hle) inhibitors, and related... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1492079