C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/51 (2006.01) C07K 14/52 (2006.01) C07K 16/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2384749
The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
L'invention concerne des polypeptides, designés ci-après par l'expression polypeptides POLYX, ainsi que des polynucléotides codant ces polypeptides POLYX, et des anticorps qui se lient de manière immunospécifique aux polypeptides POLYX ou à des polynucléotides, des dérivés, des variants, des mutants, ou encore des fragments de ceux-ci. L'invention concerne également des procédés dans lesquels les polypeptides POLYX, les polynucléotides, et les anticorps servent à détecter, prévenir et traiter une gamme importante d'états pathologiques.
Boldog Ferenc L.
Fernandes Elma
Herrmann John L.
Liu Xiaohong
Shimkets Richard A.
Curagen Corporation
Ridout & Maybee Llp
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