Novel human tissue-type plasminogen activator variant

Details Novel human tissue-type plasminogen activator variant Novel human tissue-type plasminogen activator variant

C - Chemistry, Metallurgy

12

N

167/103.33

C12N 9/72 (2006.01) A61K 38/49 (2006.01) C12N 15/00 (2006.01) C12N 15/58 (2006.01)

Patent

CA 1341609

Novel human tissue-type plasminogen activator variant that a) retains substantially full biological activity b) has a modified carbohydrate structure and c) has an altered in vivo half-life. Means for preparation of the variants and results of assays measuring function of the activators are also disclosed.

582415

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