C - Chemistry – Metallurgy – 08 – J
Patent
C - Chemistry, Metallurgy
08
J
C08J 3/075 (2006.01) C12N 5/07 (2010.01) A61K 9/10 (2006.01) A61K 47/42 (2006.01) C07K 1/14 (2006.01) C08L 89/00 (2006.01) C12N 1/00 (2006.01) C07K 1/02 (2006.01)
Patent
CA 2575522
The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self~assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions.
L'invention concerne de nouveaux hydrogels et des procédés de fabrication et d'utilisation de tels hydrogels. L'invention concerne des hydrogels susceptibles d'être formés par auto-assemblage de peptides en solution. Un tel auto-assemblage peut être constitué par modification d'une ou plusieurs caractéristiques de la solution. Les caractéristiques de la solution susceptibles d'être modifiées comprennent le pH, la résistance ionique, la température et la concentration d'un ou de plusieurs ions spécifiques. En outre, les hydrogels de cette invention peuvent être désassemblés par modification d'une ou de plusieurs caractéristiques de l'hydrogel, notamment le pH, la résistance ionique, la température et la concentration d'un ou plusieurs ions spécifiques.
Bulent Ozbas
Butterick Lisa Ann
Juliana Kretsinger
Karthikan Rajagopal
Pochan Darrin J.
Mbm Intellectual Property Law Llp
Ud Technology Corporation
University Of Delaware
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