C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 259/10 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) A61K 31/34 (2006.01) C07D 261/10 (2006.01) C07D 307/85 (2006.01) C07D 333/70 (2006.01)
Patent
CA 2521647
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
La présente invention concerne certains dérivés d'hydroxamate qui sont utiles pour le traitement de l'hépatite C. Ces composés sont également des inhibiteurs de l'histone désacétylase et sont par conséquent utiles dans le traitement de maladies liées à l'activité de l'histone désacétylase. L'invention concerne également des compositions pharmaceutiques et des procédés destinés à la préparation de ces composés.
Baskaran Chitra
Buggy Joseph J.
Robinson James
Sendzik Martin
Verner Eric J.
Axys Pharmaceuticals Inc.
Pharmacyclics Inc.
Sim & Mcburney
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