C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/21 (2006.01) A61K 39/395 (2006.01) C07K 14/57 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2507990
The present invention discloses novel open reading frames (ORFs) in human genome encoding for ORFs characterized for polypeptides having at least one activity of human Interferon gamma, and reagents related thereto including variants and fragments of said polypeptides, as well as the encoding nucleic acids and ligands directed against them. The invention provides methods for identifying and preparing these molecules, for manufacturing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
La présente invention concerne de nouveaux cadres de lecture ouverts (ORF) dans le génome humain codant pour des ORF caractérisés pour des polypeptides présentant au moins une activité de l'interféron gamma humain, des réactifs associés y compris des variantes et des fragments desdits polypeptides ainsi que les acides nucléiques codant pour ces polypeptides et des ligands dirigés contre ces derniers. Cette invention concerne également des procédés pour identifier et préparer ces molécules, pour produire des compositions pharmaceutiques contenant ces molécules et pour utiliser ces compositions dans le diagnostic, la prévention et le traitement de maladies.
Feger Georg
Ibberson Mark
Power Christine
Yorke-Smith Melanie
Applied Research Systems Ars Holding N.v.
Borden Ladner Gervais Llp
Laboratoires Serono S.a.
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