Novel imidazo[1,2-a]pyridine and imidazo[1,2-b]pyridazine...

Details Novel imidazo[1,2-a]pyridine and imidazo[1,2-b]pyridazine... Novel imidazo[1,2-a]pyridine and imidazo[1,2-b]pyridazine...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/5025 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2708361

Imidazo[1,2-a]pyridine and imidazo[1,2-b]pyridazine derivatives which inhibit Btk and are useful for the treatment of auto-immune and inflammatory diseases caused by aberrant B-cell activation, e.g. arthritis.

La présente invention concerne des dérivés d'imidazo[1,2-a]pyridine et d'imidazo[1,2-b]pyridazine qui inhibent Btk et qui sont utiles pour le traitement de maladies auto-immunes et inflammatoires causées par l'activation aberrante des lymphocytes B, par exemple l'arthrite.

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