Novel imidazo[1,2-a]pyridine derivatives, method for the...

Details Novel imidazo[1,2-a]pyridine derivatives, method for the... Novel imidazo[1,2-a]pyridine derivatives, method for the...

C - Chemistry, Metallurgy

07

D

C07D 277/82 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2730749

The invention relates to the novel products of formula (I): in which: Ra is H, Hal, aryl or heteroaryl, which are optionally substituted; Rb is H, Rc, -COORc-CO-Rc or -CO-NRcRd; where Rc is alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl, all optionally substituted; Rd is H, alk or cycloalkyl; these products being in all the isomer forms and the salts, as medicaments, in particular as MET inhibitors.

L'invention concerne les nouveaux produits de formule (I): dans laquelle: Ra représente H, HaI, aryle ou hétéroaryle éventuellement substitués; Rb représente H, Rc, -COOR c-CO-Rc ou - CO-NRcRd; avec Rc représente alkyle, cycloalkyle, hétérocycloalkyle, aryle et hétéroaryle, tous éventuellement substitués; Rd représente H, alk ou cycloalkyle; ces produits étant sous toutes les formes isomères et les sels, à titre de médicaments notamment comme inhibiteurs de MET.

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