C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/54 (2006.01) A61K 31/4164 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2493812
The invention concerns compounds of general formula (1), wherein: R1 represents a hydrogen atom, a fluorine atom or a methoxyl group (OCH¿3?), the substituent R1 on the aromatic carbocycle capable of occupying position 2, 3, 4 or 5; R2 represents a hydrogen atom or a methyl group; R3 represents a hydrogen atom, a methyl group or an ethyl group; their addition salts and optionally the hydrates of their addition salts with pharmaceutically acceptable mineral acids or organic acids as well as the isomers and the tautomers thereof.
L'invention concerne des composés de formule générale (1) dans laquelle - R1 représente un atome d'hydrogène, un atome de fluor ou un groupe méthoxyle (OCH3), le substituant RI sur le carbocycle aromatique pouvant occuper la position 2, 3, 4 ou 5 ; - R2 représente un atome d'hydrogène ou un groupe méthyle ; - R3 représente un atome d'hydrogène, un groupe méthyle ou un groupe éthyle ; leurs sels d'addition et éventuellement les hydrates des sels d'addition avec les acides minéraux ou les acides organiques pharmaceutiquement acceptables ainsi que leurs isomères et leurs tautomères.
Bonnaud Bernard
Marien Marc
Pauwels Peter
Vacher Bernard
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pierre Fabre Medicament
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