Novel imidazole derivative, pharmaceutical use thereof, and...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/14 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 401/14 (2006.01) C07D 403/02 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2109931

ABSTRACT OF THE DISCLOSURE An imidazole derivative of the formula (I) Image (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof. A method for producing the compound or its salt, and its pharmaceutical use, particularly as an agent for the prophylaxis and treatment of the diseases induced by thromboxane A2 or histamine. Also, compounds of the formula (II) and (IV) Image (II) Image (IV) wherein each symbol is as defined in the specification. The imidazole derivative and its parmacologically acceptable salt are useful as agents for the prophylaxis and treatment of the diseases induced by thromboxane A2 or histamine, and the compounds (II) and (III) are novel compounds. 7 1

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