Novel imidazole derivatives, production method thereof and...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 487/04 (2006.01) A61K 31/4188 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 233/54 (2006.01) C07D 235/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2429133

The present invention provides a compound having a steroid C17,20-lyase- inhibitory activity and useful for the therapy and prophylaxis of tumor such as prostatism, breast cancer and the like, and a method for efficiently separating an optically active compound of this compound from a mixture of optical isomers thereof, a compound of the formula:wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof, and a method for obtaining an optically active compound by optically resolving a mixture of optical isomers by the use of a resolving agent such as tartranilic acid and the like.

La présente invention se rapporte à un composé présentant une activité inhibitrice sur la C¿17,20?-lyase stéroïdienne et s'avérant utile pour le traitement thérapeutique et prophylactique d'une tumeur développée dans le cadre d'un prostatisme, d'un cancer du sein et analogue. L'invention se rapporte également à un procédé permettant de séparer efficacement une fraction optiquement active de ce composé à partir d'un mélange d'isomères optiques dudit composé. L'invention se rapporte à un composé représenté par la formule (I), dans laquelle chaque symbole est défini dans la description de l'invention, à un sel ou à un promédicament dudit composé, et à un procédé permettant d'obtenir un composé optiquement actif par résolution optique d'un mélange d'isomères optiques à l'aide d'un agent de résolution tel que l'acide tartranilique et analogue.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Novel imidazole derivatives, production method thereof and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel imidazole derivatives, production method thereof and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel imidazole derivatives, production method thereof and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1497120

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.