C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/60 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 233/66 (2006.01)
Patent
CA 2736364
Novel compounds are disclosed that have a Formula represented by the following: wherein X, R1, R2a,R2b, R2c, R3a, R3b, R4a, R4b, R4c, and ml are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non- limiting example, cachexia, osteoporosis, sarcopenia, a decline in libido and/or sexual dysfunction.
La présente invention concerne de nouveaux composés qui ont une formule représentée comme suit : où X, R1, R2a, R2b, R2c, R3a R3b, R4a, R4b, R4c, et ml sont comme présentement définis. Les composés peuvent être préparés sous la forme de compositions pharmaceutiques, et peuvent être utilisés pour la prévention et le traitement de différentes affections chez des mammifères comprenant des humains, comprenant à titre dexemple non limitatif, la cachexie, lostéoporose, la sarcopénie, une diminution de la libido et/ou un dysfonctionnement sexuel.
Blanque Roland
Deprez Pierre
Jagerschmidt Catherine
Lefrancois Jean-Michel
Namour Florence Sylvie
Galapagos Nv
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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