C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/52 (2006.01) A61K 31/27 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61K 31/675 (2006.01) C07C 279/22 (2006.01) C07D 213/77 (2006.01) C07D 233/88 (2006.01) C07D 235/30 (2006.01) C07D 239/18 (2006.01) C07D 239/42 (2006.01) C07D 249/14 (2006.01) C07D 277/50 (2006.01) C07D 471/04 (2006.01) C07F 9/547 (2006.01)
Patent
CA 2211148
Novel imino derivatives as inhibitors of bone resorption and vitronectin receptor antagonists There are described imino derivatives of the formula I R1-Y-A-B-D-E-F-G (I) in which R1, Y, A, B, D, E, F and G have the meaning indicated in the patent claims, their preparation and their use as medicaments. The compounds according to the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
Nouveaux dérivés imino, inhibiteurs de la résorption osseuse et antagonistes du récepteur de la vitronectine. On décrit des dérivés imino de formule I R1-Y-A-B-D-E-F-G (I), dans lesquels R1, Y, A, B, D, E, F et G ont la signification donnée dans les revendications du brevet; méthode de préparation et utilisation comme médicaments. Les composés de l'invention sont utilisés comme antagonistes du récepteur de la vitronectine et comme inhibiteurs de la résorption osseuse.
Bodary Sarah Catherine
Carniato Denis
Gadek Thomas Richard
Gourvest Jean-Francois
Knolle Jochen
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Genentech Inc.
Hoechst Aktiengesellschaft
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