C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 39/095 (2006.01) A61K 39/395 (2006.01) C07K 16/12 (2006.01) C12N 5/12 (2006.01) C12N 5/16 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2522751
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
La présente invention concerne des protéines ORF2086 de <i>Neisseria </i>, des protéines immunogènes à réaction croisée lesquelles peuvent être isolées de souches de Neisseria ou préparées par recombinaison, notamment leurs parties immunogènes, leurs équivalents biologiques, des anticorps se fixant de manière immunospécifique aux éléments précités ainsi que des séquences nucléotidiques codant chacun des éléments précités, ainsi que l'utilisation de celles-ci dans des composition immunogènes efficaces contre des infections due à <i>Neisseria meningitidis </i> sérogroupe B.
Bernfield Liesel A.
Farley John
Fletcher Leah D.
Metcalf Benjamin J.
Zagursky Robert J.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Wyeth Holdings Corporation
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