C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/095 (2006.01) A61K 39/40 (2006.01) C07K 1/00 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2463476
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
la présente invention concerne des protéines Neisseria ORF2086, des protéines immunogènes à réaction croisée pouvant être isolées à partir de souches de Neisseria ou par recombinaison, dont des parties immunogènes de ces protéines, des équivalents biologiques de ces protéines, des anticorps qui se lient en mode immunopécifique auxdites protéines et des séquences d'acides nucléiques codant chacune pour ces protéines, ainsi que l'utilisation desdites protéines dans des compositions immunogènes efficaces contre l'infection par le sérogroupe B de Neisseria meningitidis.
Bernfield Liesel A.
Farley John
Fletcher Leah D.
Metcalf Benjamin J.
Zagursky Robert J.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Wyeth Holdings Corporation
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