Novel immunogenic compositions for the prevention and...

Details Novel immunogenic compositions for the prevention and... Novel immunogenic compositions for the prevention and...

A - Human Necessities

61

K

A61K 39/00 (2006.01)

Patent

CA 2673515

The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.

La présente invention porte sur des protéines de ORF2086 de Neisseria, des protéines immunogènes à réaction croisée qui peuvent être isolées à partir de souches neisseriales ou préparées de façon recombinante, comprenant des parties immunogènes de celles-ci, des équivalents biologiques de celles-ci, des anticorps qui se lient de façon immunospécifique aux précédent(e)s et des séquences d'acide nucléique codant chacun(e) des précédent(e)s. L'invention porte également sur l'utilisation des précédent(e)s dans des compositions immunogènes qui sont efficaces contre une infection par Neisseria meningitidis sérogroupe B.

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