A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2739387
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
L'invention concerne des peptides, des acides nucléiques et des cellules à utiliser dans des procédés immunothérapeutiques. En particulier, l'invention concerne l'immunothérapie du cancer. L'invention concerne également des épitopes peptidiques de lymphocytes T cytotoxiques associés à une tumeur, seuls ou combinés à d'autres peptides associés à une tumeur, qui servent de principes actifs pharmaceutiques de compositions de vaccin qui stimulent des réactions immunitaires anti-tumorales. L'invention concerne 30 séquences peptidiques et leurs variants dérivés de molécules HLA de classe I et de classe II de cellules tumorales humaines, qui peuvent être utilisés dans des compositions de vaccin pour éliciter des réponses immunitaires anti-tumorales.
Hilf Norbert
Schoor Oliver
Singh Harpreet
Trautwein Claudia
Walter Steffen
Heenan Blaikie Llp
Immatics Biotechnologies Gmbh
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