Novel in vitro methods for studying receptors recognizing...

G - Physics – 01 – N

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G01N 33/566 (2006.01)

Patent

CA 2597241

The present invention in particular relates to in vitro methods to identify and/or confirm the binding and/or function of a volatile compound onto a membrane-integrated receptor using volatile-compound-Binding Protein (BP) or compositions thereof. Additionally, the present invention relates to kits comprising receptor proteins recognizing volatile compounds or a candidate receptor for said compound; and; BP, a complex or a composition thereof. Said kits may be used to identify and/or confirm the binding and/or function of volatile compounds onto a membrane-integrated receptor.

La présente invention concerne des méthodes in vitro destinées à l'identification et/ou à la confirmation de la fixation et/ou de la fonction d'un composé volatile sur un récepteur intégré dans une membrane à l'aide d'une protéine de liaison (BP) fixant un composé volatil ou de compositions associées. La présente invention concerne également des trousses comprenant des protéines réceptrices reconnaissant des composés volatils ou un récepteur candidat pour ledit composé ; and ; BP, un complexe ou une composition associée. Ces trousses peuvent être utilisées pour identifier et/ou confirmer la fixation et/ou la fonction de composés volatils sur un récepteur intégré dans une membrane.

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