C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/18 (2006.01) A61K 31/405 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/422 (2006.01) A61K 31/427 (2006.01) A61K 31/433 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2620658
The invention relates to indole derivative compounds having general formula (I) as defined in the claims and to the pharmaceutically-acceptable addition salts thereof. The invention also relates to the method of preparing the aforementioned compounds, to pharmaceutical compositions containing same and to the use thereof as a pharmacologically-active substance, for example in the treatment of hypertriglyceridaemias, hyperlipidemias, hypercholesterolemias, diabetes, endothelial dysfunction, cardiovascular and inflammatory diseases and neurodegeneration.
L'invention concerne des composés dérivés d'indole de formule générale (I) : telle que définie dans les revendications, et leurs sels d'addition pharmaceutiquement acceptable. Elle concerne également leur procédé de préparation, les compositions pharmaceutiques les contenant, et leur utilisation en tant que substance pharmacologiquement active, notamment dans le traitement des hypertriglycéridémies, des hyperlipidémies, des hypercholestérolémies, du diabète, de la dysfonction endothéliale, des maladies cardiovasculaires, inflammatoires et des neurodégénérescences.
Barth Martine
Binet Jean
Boubia Benaissa
Dodey Pierre
Legendre Christiane
Laboratoires Fournier S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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