Novel inhibitors of bone reabsorption and antagonists of...

Details Novel inhibitors of bone reabsorption and antagonists of... Novel inhibitors of bone reabsorption and antagonists of...

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61K 31/675 (2006.01) C07D 233/78 (2006.01) C07D 233/96 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 471/02 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 491/056 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2199923

The present invention relates to 5-membered ring heterocycles of the formula I, (See fig. I) in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments. The novel compounds are used as vitronectin receptor antagonists and as inhibitors of bone reabsorption.

Hétérocycles à noyau de 5 chaînons, de formule I (voir fig. I), dans laquelle E, F, G, W, Y et Z ont la signification spécifiée dans les revendications du brevet; méthode pour les préparer et leur emploi comme médicaments. Les nouveaux composés sont utilisés comme antagonistes du récepteur de la vitronectine et comme inhibiteurs de la réabsorption osseuse.

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