C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 263/34 (2006.01) A61K 31/42 (2006.01) C07D 263/32 (2006.01) C07D 307/20 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2348267
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune disease.
La présente invention porte sur l'identification de nouveaux inhibiteurs d'IMPDH (inosine-5'-monophosphate déshydrogénase). L'invention porte également sur des composés et des compositions pharmaceutiques utiles dans le traitement ou la prévention des troubles associés à IMPDH tels que le rejet de transplants et les maladies auto-immunes.
Dhar T. G. Murali
Gu Henry H.
Iwanowicz Edwin J.
Bristol-Myers Squibb Company
Dimock Stratton Llp
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