C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 69/757 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) C07C 61/29 (2006.01) C07C 61/35 (2006.01) C07C 69/753 (2006.01)
Patent
CA 2372962
Compounds are disclosed that have the chemical structure of Formula (II) and (IIB) and their produg esters and acid-addition salts, and that are useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of various diseases, wherein the R groups are defined in the claims.
L'invention concerne des composés ayant la structure chimique des formules (II) et (IIB) ainsi que leurs esters et sels d'addition d'acide de promédicaments, lesquels sont utiles en tant que modulateurs de l'interleukine-1 et du facteur de nécrose tumorale alpha et sont par conséquent utiles dans le traitement de diverses maladies, les groupes R étant définis dans les revendications.
Palladino Michael
Theodorakis Emmanuel A.
Barrigar Intellectual Property Law
Nereus Pharmaceuticals Inc.
The Regents Of The University Of California
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