Novel intermediates and their use to prepare n,n'-bridged...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/22 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2237401

This invention provides compounds of formula (II). The invention further provides the use of this compound to prepare N,N'-bridged bisindolylmaleimides. Furthermore, the invention provides pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.

L'invention concerne des composés présentant la formule (II). En outre, l'invention prévoit l'utilisation de ce composé dans la préparation des bisindolylmaléimides pontés en N, N'. De plus, l'invention traite de formulations pharmaceutiques et des procédés d'utilisation pour inhiber la protéine kinase C chez le mammifère.

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