Novel iridoid derivatives and neovascularization inhibitors...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 493/04 (2006.01) A61K 31/335 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07D 303/16 (2006.01) C07D 311/94 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 493/10 (2006.01)

Patent

CA 2248725

Novel iridoid derivatives respresented by general formulae (I), (II), (V), (VI), (VIII), etc., and neovascularization inhibitors containing the same as the active ingredient, which exhibit remarkable neovascularization inhibitory effects without being accompanied with serious side effects, thus being useful for curing and preventing various diseases accompanied with abnormally increased neovascularization.

L'invention concerne de nouveaux dérivés iridoïdes représentés par les formules générales (I), (II), (V), (VI), (VIII), etc, ainsi que des inhibiteurs de la néovascularisation contenant ceux-ci en tant qu'ingrédients actifs. Ces dérivés sont des inhibiteurs remarquables de la néovascularisation et ils n'ont pas d'effets secondaires sérieux. Ils sont donc utiles pour guérir et prévenir différentes maladies accompagnées par une augmentation anormale de la néovascularisation.

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