C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01)
Patent
CA 2325359
Novel LRSG polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length LRSG proteins, the invention further provides isolated LRSG fusion proteins, antigenic peptides and anti-LRSG antibodies. The invention also provides LRSG nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an LRSG gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Cette invention concerne des polypeptides, des protéines et des molécules d'acide nucléique LRSG. En plus des protéines LRSG complètes isolées, l'invention concerne des protéines de fusion LRSG isolées, des peptides antigéniques et des anticorps anti-LRSG. De plus, cette invention concerne des molécules d'acide nucléique LRSG, des vecteurs d'expression recombinants renfermant les molécules d'acide nucléique selon l'invention, des cellules hôtes dans lesquels ont été introduits les vecteurs d'expression, et des animaux transgéniques non humains chez lesquels le gène LRSG a été introduit ou invalidé. Sont également présentées des méthodes de diagniostic, de recherche systématique et de traitement faisant intervenir lesdites compositions.
Borden Ladner Gervais Llp
Millennium Pharmaceuticals Inc.
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