Novel macrocyclic peptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/64 (2006.01) A61K 38/13 (2006.01)

Patent

CA 2724523

Disclosed are cyclosporine derivatives in which the 3-Sarcosine carbon and 5- Valine nitrogen are each substituted by a non-hydrogen substituent, and their use as pharmaceuticals, in particular for the treatment of hepatitis C virus.

La présente invention concerne des dérivés de cyclosporine dans lesquels le carbone de la sarcosine-3 et lazote de la valine-5 sont chacun substitués par un substituant non-hydrogène, et leur utilisation en tant quagents pharmaceutiques, en particulier pour le traitement du virus de lhépatite C.

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