C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2420932
The present invention relates to a novel nuclear receptor called "L66" or also FXR-.beta. a homologue of the FXR-.alpha., a prototypical type 2 nuclear receptor. The invention also relates to the isolated nucleic acid sequence of L66 and the isolated protein thereof. The invention further relates to processes for isolating and/or producing the nucleic acid or the protein as well as methods of use of the receptor L66.
La présente invention concerne un nouveau récepteur nucléaire appelé <= L66 >= ou également FXR-.beta., un homologue de FXR-.alpha., un prototype de récepteur nucléaire de type 2. L'invention concerne également la séquence d'acide nucléique isolée de L66 et la protéine isolée liée à la séquence d'acide nucléique isolée. L'invention concerne également des procédés permettant d'isoler et/ou de produire cet acide nucléique ou cette protéine, ainsi que des méthodes d'utilisation de ce récepteur L66.
Casari Georg
Hofer Michael
Jackson David
Kranz Harald
Otte Kerstin
Gowling Lafleur Henderson Llp
Lion Bioscience Ag
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