Novel markers for alternatively activated macrophages

G - Physics – 01 – N

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G01N 33/50 (2006.01)

Patent

CA 2538189

The present invention relates to novel markers for alternatively activated macrophages. More specifically, the present invention relates to the use of galactose-type C-type lectins as surface markers, that allows rapid identification and sorting of the alternative macrophages. Such identifications can be useful in diseases where there is an imbalance between proinflammatory and anti-inflammatory immune reactions.

L'invention concerne de nouveaux marqueurs destinés à des macrophages activés en alternance. Plus précisément, l'invention concerne l'utilisation de lectines de type C de type galactose en tant que marqueurs de surface, qui permet une identification rapide et un tri des macrophages de substitution. Ces identifications peuvent servir dans des maladies où il y a un déséquilibre entre les réactions immunitaires proinflammatoires et anti-inflammatoires.

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