Novel mch receptor antagonists

Details Novel mch receptor antagonists Novel mch receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 263/58 (2006.01) C07D 277/68 (2006.01) C07D 277/82 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2589678

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein Ar1, L1, R1, q, X, R2, R3, R4, and R5 are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

L'invention concerne un composé antagoniste de l'hormone concentrant la mélanine (MCH) représenté par la formule (I), ou un sel, un solvate ou un énantiomère acceptable sur le plan pharmaceutique de ce composé, utile dans le traitement, la prévention et le soulagement des symptômes associés à l'obésité ou à des maladies connexes. Dans la formule (I), Ar1, L1, R1, q, X, R2, R3, R4, et R5 sont tel que définis dans la description.

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