C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C07K 14/705 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2322055
The invention concerns a novel mechanically sensitive potassium channel family activated by polyunsaturated fatty acids in particular by arachidonic acid and by riluzole. The invention also concerns a method for screening a substance capable of modulating the ionic currents of said channels.
La présente invention concerne une nouvelle famille de canaux potassium mécanosensibles activés par les acides gras polyinsaturés notamment l'acide arachidonique et par le riluzole. L'invention se rapporte aussi au procédé de criblage de substance susceptible de moduler les courants ioniques desdits canaux.
Duprat Fabrice
Fink Michel
Honore Eric
Lazdunski Michel
Lesage Florian
Centre National de La Recherche Scientifique (c.n.r.s.)
Gowling Lafleur Henderson Llp
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