C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/12 (2006.01) C07K 7/08 (2006.01) C07K 7/64 (2006.01)
Patent
CA 2530027
The present invention relates to novel chimeric peptides and templates containing a combination of antagonist and agonist endogenous ligand residues. In particular, the present invention relates to novel chimeric peptides and templates thereof based upon melanocortin agonist peptides and agouti related protein (AGRP). The present invention provides multifunctional chimeric peptides having specific bioactivity at melanocortin receptors and their use as drugs to treat various diseases and conditions.
L'invention concerne de nouveaux peptides chimères et des matrices contenant une combinaison de résidus de ligands endogènes antagonistes et agonistes. D'une manière plus spécifique, l'invention concerne de nouveaux peptides chimères et leurs matrices basées sur des peptides agonistes de la mélanocortine et une protéine AGRP (agouti related protein). L'invention concerne des peptides chimères multifonctionnels présentant une bioactivité spécifique au niveau des récepteurs de la mélanocortine et leur utilisation en tant que médicaments pour traiter diverses maladies et affections.
Mbm Intellectual Property Law Llp
University Of Florida
University Of Florida Research Foundation Incorporated
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