C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/415 (2006.01) A61K 31/50 (2006.01) A61K 31/55 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2133963
The present invention relates to certain novel mercaptoacetylamido pyridazo[1,2]pyridazine, pyrazolo[1,2]pyridazine, pyridazo[1,2-a][1,2]diazepine and pyrazolo[1,2-a][1,2]diazepine derivatives of formula (I) useful as inhibitors of enkephalinase and of ACE.
La présente invention concerne certains nouveaux dérivés de mercaptoacétylamido-pyridazo[1,2]pyridazine, de pyrazolo[1,2]pyridazine, de pyridazo[1,2-a][1,2]diazépine et de pyrazolo[1,2-a][1,2]diazépine de formule (I) utiles comme inhibiteurs de l'enképhalinase et de l'enzyme de conversion de l'angiotensine.
Flynn Gary A.
Shum Patrick W.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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