C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 3/06 (2006.01) A61K 31/555 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2308317
Invented are zinc chelated dimeric cell-surface receptor ligands, pharmaceutical compositions containing these compounds, and methods of using these compounds as agonist of dimeric cell-surface receptors. Also invented are novel processes used in preparing these compounds. Also invented are novel receptor binding moieties of the invented zinc chelated cell-surface receptor ligands.
L'invention concerne des ligands à chélation de zinc de récepteurs dimères de surface cellulaire, des compositions pharmaceutiques contenant ces composés et des méthodes consistant à utiliser ces composés comme agonistes des récepteurs dimères de la surface cellulaire. L'invention concerne en outre de nouveaux procédés permettant de préparer ces composés, ainsi que de nouvelles fractions fixatrices présentes dans les ligands à chélation de zinc de récepteurs de surface cellulaires décrits.
Gleason John Gerald
Luengo Juan I.
Gleason John Gerald
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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