Novel method for synthesis of (2s, 3as,...

Details Novel method for synthesis of (2s, 3as,... Novel method for synthesis of (2s, 3as,...

C - Chemistry, Metallurgy

07

K

C07K 5/02 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2455706

The invention concerns a method for industrial synthesis of compounds of formula (I), wherein: R¿1? represents a hydrogen atom or a linear or branched C¿1?-C¿6? alkyl group or benzyl, and R¿2? represents a group protecting the amino function. The invention also concerns the use of same for industrial synthesis of perindopril of formula (II) and its pharmaceutically acceptable salts.

Procédé de synthèse industrielle des composés de formule (I) dans laquelle R1 représente un atome d'hydrogène ou un groupement alkyle ou benzyle, et R2 représente un groupement protecteur de la fonction amino. Application à la synthèse du perindopril et de ses sels pharmaceutiquement acceptables.

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