Novel method for the diastereoselective production of a...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 41/00 (2006.01)

Patent

CA 2670655

The invention relates to a diastereoselective method for obtaining a primary amine on a steroid, comprising the reduction of an oxime by lithium in ammonia at a low temperature in an ether/alcohol mixture.

La présente invention a pour objet un procédé diastéréosélectif pour l'obtention d'une aminé primaire sur un stéroïde, consistant à réduire un oxime par le lithium dans l'ammoniac à basse température dans un mélange éther-alcool.

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