C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/04 (2006.01) A61K 39/02 (2006.01) A61K 39/095 (2006.01) A61K 39/102 (2006.01) A61K 39/385 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2278626
The invention relates to a method for the isolation of polysaccharides, in particular for the separation of endotoxins from capsule polysaccharides of gram-negative bacteria. The polysaccharides isolated by this method are preferably used for the production of polysaccharide vaccines. The invention furthermore relates to vaccines containing polysaccharides isolated by the method described in this invention.
L'invention concerne un nouveau procédé pour isoler des polysaccharides, notamment pour séparer des endotoxines situées dans des polysaccharides encapsulées de bactéries Gram négatif. Les polysaccharides isolées à l'aide dudit procédé s'utilisent de préférence pour préparer des inoculants de saccharide. L'invention concerne en outre des inoculants contenant des polysaccharides isolées à l'aide dudit procédé.
Furer Emil
Hasler Thomas
Crucell Switzerland Ag
Mccarthy Tetrault Llp
Schweiz. Serum- & Impfinstitut Bern
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