Novel method of preparing nitrogen macrocycles

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 257/02 (2006.01) C07D 235/00 (2006.01) C07D 239/00 (2006.01) C07D 241/00 (2006.01) C07D 487/08 (2006.01) C07D 487/18 (2006.01) C07D 487/22 (2006.01)

Patent

CA 2461344

The invention relates to a method of preparing nitrogen macrocycles having formula (I). The inventive method comprises a step involving the reaction of compounds (II) and (III) in order to form a compound having formula (IV). Said compound is subsequently made to react with a compound having formula (V) in order to form a compound having formula (VI). The latter compound is then subjected to an acid treatment.

La présente invention concerne un procédé de préparation de macrocycles azotés de formule (I), une étape de réaction des deux composés (II) et (III) suivants pour former un composé de formule (IV), qu'on fait ensuite réagir avec un composé de formule (V) pour former un composé de formule (VI), qu'on soumet ensuite à un traitement acide.

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