Novel method of treating hyperlipidemia

A - Human Necessities – 61 – K

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A61K 31/366 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/553 (2006.01) A61K 45/06 (2006.01) A61P 1/16 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2609784

A pharmaceutical composition useful for the prevention and/or treatment of hyperlipidemia, which comprises combining an effective amount of a squalene synthase inhibitor and a HMG-CoA reductase inhibitor is provided. Furthermore, a method for preventing and / or treating hepatic toxicity caused by the administration of a HM6-C0A veductase inhibitor, which comprisis adminisvering an effective amount of a sgualence synthase inhibitor, is provided .

L'invention porte sur une composition pharmaceutique utile dans la prévention et/ou le traitement de l'hyperlipidémie. Cette composition comprend une combinaison d'une quantité efficace d'un inhibiteur de la squalène synthase et d'un inhibiteur de la HMG-CoA réductase.

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