Novel methods and medicament for treating infectious...

A - Human Necessities – 61 – K

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Details

A61K 38/44 (2006.01) A61K 38/18 (2006.01) A61K 38/40 (2006.01) A61K 38/46 (2006.01) A61K 38/47 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2377674

The present invention provides the novel use of peroxidases, lactoferrin, lactoferrin peptides, lysozymes and immunoglobulins (used alone and/or combined) for the control of microbial biofilms after the action of growth factors (used alone and/or combined) on the epithelial and fibroblast cells to remove micro-organism biofilms adherent on cell surfaces. The present invention also relates to the use of peroxidases, lactoferrin, lactoferrin peptides, lysozymes and immunoglobulins (used alone and/or combined) in combination with growth factors (used alone and/or combined) for the preparation of medicaments for the prophylaxis or therapy of infectious diseases caused by microorganisms present in biofilms adherent on cell surfaces.

L'invention concerne la nouvelle utilisation de peroxydases, lactoferrine, de peptides de lactoferrine, de lysozymes et d'immunoglobulines (utilisés seuls et/ou combinés) pour la commande de biofilms microbiens après l'action de facteurs de croissance (seuls et/ou combinés) sur les cellules épithéliales et fibroblastes de manière à supprimer les biofilms de micro-organismes adhérant aux surfaces des cellules. L'invention concerne aussi l'utilisation de peroxydases, de lactoferrine, de peptides de lactoferrine, de lysozymes et d'immunoglobulines (utilisés seuls et/ou combinés) combinés à des facteurs de croissance (seuls et/ou combinés) pour la préparation de médicaments de prévention ou de traitement des maladies infectieuses causées par ces micro-organismes se trouvant dans les biofilms adhérant aux surfaces des cellules.

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