Novel methods and reagents directed to production of cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/0775 (2010.01) C12N 5/0735 (2010.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2676323

The present invention provides methods and mate rials to modulate and grow stem cells by contacting stem cells with a binder recognizing te rminal glycan structures of stem cells. The modulation can be morphological change, change in differentiation status, biological status or adherence. The materials provided in the present invention are also useful to screen such a binding agents and binders.

La présente invention porte sur des procédés et des matières pour moduler et développer des cellules souches par la mise en contact des cellules souches avec un liant reconnaissant les structures de glycane terminales des cellules souches. La modulation peut être un changement morphologique ou d'état de différenciation, un état biologique ou une adhérence. Les matières fournies dans la présente invention sont également utiles pour cribler de tels agents de liaison et de tels liants.

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