Novel methods for the preparation of taxanes using...

C - Chemistry – Metallurgy – 07 – D

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C07D 305/14 (2006.01) C07C 229/34 (2006.01) C07C 233/87 (2006.01) C07D 263/04 (2006.01) C07D 263/52 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2170661

Novel oxazolidines finding utility as intermediates in the preparation of C-13 acyloxy sidechain-bearing taxanes such as paclitaxel and analogs thereof. The present invention also relates to novel methods of coupling the oxazolidines to form the aforementioned taxanes, and to methods of preparing the oxazolidines.

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