Novel methylenebisphosphonic acid derivatives

Details Novel methylenebisphosphonic acid derivatives Novel methylenebisphosphonic acid derivatives

C - Chemistry, Metallurgy

07

F

C07F 9/40 (2006.01) A61K 31/66 (2006.01) C07F 9/547 (2006.01) C07F 9/58 (2006.01)

Patent

CA 2098735

Novel pharmacologically active methylenebisphosphonates having formula (I) wherein R1-R4 independently are C1-C10-alkyl, C3-C10-cycloalkyl, aryl, aralkyl, silyl SiR3 or hydrogen, whereby in formula (I) at least one of the groups R1-R4 is hydrogen and at least one of the groups R1-R4 is different from hydrogen; Q1 is hydrogen, hydroxyl, halogen, ami- no NH2, or OR'1, wherein R'1 is C1-C4-alkyl or acyl; Q2 is the group,(.alpha.) wherein Y is a six-membered heterocyclic group, or a carbocyclic aromatic group, X is a bond, O, S or NR"', wherein R"' is hydrogen, lower alkyl, or acyl, n is the integer 0 to 6, and R' and R" are hydrogen or lower alkyl provided that as a ring atom of the ring Y and/or a chain atom of the group X, there is always at least one heteroatom from the group of O, N and S, including the stereoisomers and the salts of the compounds.

Affiliated with

Also associated with

Rating

Novel methylenebisphosphonic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel methylenebisphosphonic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel methylenebisphosphonic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1719636